Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.
'Newsweek' reports that scientists have uncovered
a genetic variant that has the potential to reduce
the odds of developing Alzheimer's by as much as 70%.
The discovery could reportedly lead to new methods to
effectively treat or prevent the disease which impacts
approximately 5.8 million people in the United States alone.
Some genetic variants have been found to have an
association with an increased likelihood of developing
the disease, while other variants offer protection. .
A team from Columbia University found that
genes involved with the production of fibronectin
play a crucial role in developing Alzheimer's.
Healthy individuals usually only have fibronectin present
in small amounts along their blood-brain barrier, while
those with Alzheimer's have much higher quantities.
It's a classic case of too much
of a good thing. It made us think
that excess fibronectin could be
preventing the clearance of [abnormal
protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of
neurological sciences at Columbia University's Vagelos
College of Physicians and Surgeons, via 'Newsweek'.
The team believes that methods aimed at reducing
fibronectin could play a crucial role in developing
new treatments and preventative measures. .
Anything that reduces excess
fibronectin should provide some
protection, and a drug that does
this could be a significant step
forward in the fight against
this debilitating condition, Caghan Kizil, co-leader of the study and professor of
neurological sciences at Columbia University's Vagelos
College of Physicians and Surgeons, via 'Newsweek'.
Our findings suggest that...
we may be able to develop new
types of therapies that mimic
the gene's protective effect
to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of
neurological sciences at Columbia University's Vagelos
College of Physicians and Surgeons, via 'Newsweek'.
The Columbia University team's
findings were published in the
journal 'Acta Neuropathologica.'
Credit: Wibbitz Top Stories Duration: 01:31Published
Biden Campaign to Rake In $25 Million , at Star-Studded Fundraiser.
President Biden will host the
most lucrative political fundraiser in
American history on March 28, Politico reports. .
The event will feature former
Presidents Barack Obama and Bill Clinton.
The event will feature former
Presidents Barack Obama and Bill Clinton.
Mindy Kaling will emcee the event
from Radio City Music Hall.
There will be musical performances by
Cynthia Erivo, Queen Latifah, Lizzo.
There will be musical performances by
Cynthia Erivo, Queen Latifah, Lizzo.
There will be musical performances by
Cynthia Erivo, Queen Latifah, Lizzo.
Lea Michele and Ben Platt.
Lea Michele and Ben Platt.
Stephen Colbert will host an "armchair conversation" with Biden, Obama and Clinton.
Unlike our opponent, every dollar weâre raising
is going to reach the voters who will decide
this election â communicating the presidentâs
historic record, his vision for the future and
laying plain the stakes of this election, Jeffrey Katzenberg, the Biden campaign co-chair, via statement.
The numbers donât lie: todayâs event
is a massive show of force and a
true reflection of the momentum
to reelect the Biden-Harris ticket, Jeffrey Katzenberg, the Biden campaign co-chair, via statement.
$25 million is expected to be raised at the event. .
By comparison, Biden's campaign raised
$21 million during all of last month.
Meanwhile, former President Donald Trump
raised $20 million during the month of February.
Credit: Wibbitz Top Stories Duration: 01:31Published
As "IF" Ryan Reynolds' looks over the years could get any HOTTER ... Here is a 21-year-old version of the hilarious Hollywood hottie at the "Two Guys And A Girl".. TMZ.com
Gayle King is dishing on how she got cover ready for her photo shoot with Sports Illustrated ... giving cred to the very company her pal Oprah Winfrey just.. TMZ.com
The summer Olympics are right around the corner, and Snoop D.O. Double G is hoping for a perfect 10.0 from you! Show this rap icon what a star he is by scoring.. TMZ.com
Steve Buscemi's alleged attacker has been arrested in NYC -- and cops say they picked him up after responding to a call at a homeless shelter ... TMZ has.. TMZ.com
Donald Trump took a break from his NYC criminal trial and presidential campaign to celebrate a major milestone ... his son Barron's high school graduation. The.. TMZ.com
Russia plans to exhibit captured British and NATO military vehicles in Moscow for Victory Day celebrations, showcasing 30 vehicles from 12 nations, including German and American tanks seized in Ukraine. The exhibition, set in Victory Park, marks a shift from commemorating World War II to celebrating Russia's invasion of Ukraine. Social media footage and unverified videos depict the display of captured Western military hardware.
#Russia #USAbramTanks #NATO #Moscow #VictoryDayCelebrations #VladimirPutin #VolodymyrZelensky #Worldnews #Biden #Oneinda #Oneindia news
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Intense clashes between Russian and Ukrainian forces result in tragedy as at least 10 people are killed in frontline regions. With Russian forces intensifying their offensive in the eastern Donetsk region ahead of May 9th, tensions escalate amidst commemorations of World War II. Stay informed on the latest developments in this volatile situation.
#RussiaUkraineWar #RussianStrikes #UkrainianStrikes #RussiaAttacksUkraine #UkraineAttacksRussia #FrontlineRegions #Oneindia
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King Charles is already topping his late mother, the beloved Queen Elizabeth II, in one major way ... thanks to some superior financial planning. The Sunday.. TMZ.com
Sons of Paul McCartney and John Lennon , Release New Song âPrimrose Hillâ.
James McCartney and
Sean Ono Lennon co-wrote the
song "Primrose Hill" which
was released on April 12. .
âPrimrose Hillâ is here! Today I am
so very excited to share my latest
song co-written by my good
friend @sean_ono_lennon. , James McCartney, via Instagram.
âPrimrose Hillâ is here! Today I am
so very excited to share my latest
song co-written by my good
friend @sean_ono_lennon. , James McCartney, via Instagram.
With the release of this song it
feels like weâre really getting the
ball rolling and I am so excited to
continue to share music with you, James McCartney, via Instagram.
McCartney took to X on April 2
to tease the song's release.
I had a vision as a child in Scotland,
on what was a lovely summerâs day.
Letting go, I saw my true love and
saviour in my mindâs eye. , James McCartney, via X.
âPrimrose Hillâ is about getting the ball
rolling with me & finding this person, James McCartney, via Instagram.
James' father, Paul McCartney,
also promoted the song.
My son James has a new song out
called âPrimrose Hillâ â check it
out! And lots of love to Sean Ono
Lennon who co-wrote the song, Paul McCartney, via Facebook.
James is holding a contest for couples to be featured in the video for "Primrose Hill.".
Couples who wish to enter must submit videos of themselves capturing their love in the favorite place.
Submissions, due April 19, must play "Primrose Hill" in the background
Credit: Wibbitz Top Stories Duration: 01:30Published
This Day in History: , Paul McCartney Announces
the Breakup of the Beatles.
April 10, 1970.
McCartney announced the breakup
in a press statement prior to the release
of his debut solo album, 'McCartney.'.
When asked if his songwriting partnership
with John Lennon would be active again,
McCartney replied with a terse, "No.".
The Beatles had been in the process
of breaking up for several years.
But the statement sent shockwaves
through the music industry, further alienating
McCartney from the rest of the band.
In an interview with 'Rolling Stone,'
Lennon responded, saying, "[Paul] canât
have his own way, so heâs causing chaos.".
By the end of 1970, McCartney officially
filed suit to dissolve the
business partnership of The Beatles
Credit: Wibbitz Top Stories Duration: 00:53Published
Warner Bros. has finally dropped the first trailer for the highly anticipated 'Joker' sequel, 'Joker: Folie Ă Deux.' The studio unveiled the clip while at CinemaCon where theater owners were given a glimpse of Joaquin Phoenix and Lady Gaga together in terrifying action.
Credit: The Hollywood Reporter Duration: 01:17Published
Happy Birthday,
Lady Gaga!.
Stefani Joanne Angelina Germanotta
turns 38 years old today.
Here are five fun facts
about the singer.
1. Gaga is the only woman who had
five No. 1 albums in the 2010s.
2. Her stage name
was inspired by
the Queen song,
âRadio Gaga.â.
3. She wrote her hit
single, âBorn This Way,â
in 10 minutes.
4. Gaga signed a record deal with Interscope Records on her 20th birthday.
5. Her favorite cartoon character
is Bugs Bunny.
Happy Birthday,
Lady Gaga!
Credit: Wibbitz Top Stories Duration: 00:50Published